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CagriSema treatment resulted in substantially greater and clinically meaningful weight loss (-20.4%) than semaglutide alone (-14.9%), cagrilintide alone (-11.5%), or placebo (-3.0%), a finding consistent with at least partial additivity, although the study design does not permit a formal assessment of additive or synergistic effects

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Following current clinical guidelines, we typically consider Tirzepatide as a potential weight management treatment option for adults with a body mass index (BMI) of 30 or greater, indicating obesity

Lennicke, C

Jan 1996;11(1):55-62